Agnes matched her sister in devotion to prayer and in willingness to endure the strict penances that characterized the Poor Ladies’ lives at San Damiano. In 1221, a group of Benedictine nuns in Monticelli near Florence asked to become Poor Ladies. Saint Clare sent Agnes to become abbess of that monastery. Agnes soon wrote a rather sad letter about how much she missed Clare and the other nuns at San Damiano. After establishing other monasteries of Poor Ladies in northern Italy, Agnes was recalled to San Damiano in 1253, as Clare lay dying.
Three months later Agnes followed Clare in death, and was canonized in 1753.